Multifunctional Synthesizer
The PET-IF B-FC N multifunctional automated synthesis instrument
Category：
Radiopharmaceutical synthesizer
Key words：
multifunctional
interface
equipped
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Product description
PET-IF B-FC N multifunctional synthesizer
The PET-IF B-FC N multifunctional automated synthesis instrument is computer-controlled and equipped with semi preparative HPLC, which can be quickly separated and purified in combination with SPE. It can also be used for the clinical and scientific preparation of F, 1C, and 1N radiolabeled drugs. It can also be used for the preparation of 64Cu, 68Ga, 89Zr, 90Y, 99mTc, 124I, 177Lu, 211At, 225Ac and other radiolabeled drugs. Equipped with an online Triflate reactor, it can prepare a large number of drugs and synthesize many scientific drugs, such as FDOPA. The user interface is simple and easy-to-use, with drag and drop interface editing, and users can freely edit the new drug interface according to their needs.
System features
Double reaction tube
Online Triflate Reactor
Equipped with semi preparative HPLC
Full wavelength ultraviolet detector
Online concentration and purification
Highly flexible operating modes (fully automatic, semi-automatic, and manual)
Powerful research programming capabilities and hardware support
Extremely high reliability
High synthesis efficiency (18F-FDG uncorrected synthesis efficiency⩾70%)
Compliant with GMP requirements
TECHNICAL INDEX
The complete set of equipment includes:
1 synthesizer
1 controller
1 control computer and 1 set of control software
Appearance dimensions:
Synthesizer: 350x510x400mm (height x width x depth) (placed in a hot room)
Controller: 220x355x400mm (height x width x depth) (placed outdoors)
HPLC (pump and UV): built-in
Temperature control system:
Heating rate: 25 ℃ to 120 ℃, time 10s to 2s
Temperature accuracy: error<3%
Cooling rate: 120 ℃ to 50 ℃, time 25s ± 2s
Temperature accuracy: error<3%
Interlocking: Hardware and Software
Reaction system:
Reaction system: closed type
Number of heaters: 4
Number of reactors: 3 (including 1 Tr if late reactor)
Radioactive detector:
Type of radioactive detector: GM counter tube or semiconductor
Number of radioactive detectors: 6 or more
Detection range: 1mci~3C
Detection accuracy: error<10%
Typical production varieties and yields (compliant with GMP):
18F-FDG
FDG uncorrected synthesis efficiency: 70 ± 5%
FDG radiochemical purity: ⩾ 99.0%
FDG synthesis time: ≤ 25min
18F-PSMA, 18F-NAF, 18F-AV45, 18F-DOPA, 18F-FDDNP, 18F-FETNIM, 18F-FES, 18F-FECH, 18F-FLT, 18F-FECH, 18F-SFB, 18F Octreotide, 18F-MPPF, 18F-FP - β - CIT, 18F-FET, 18F-FMISO, 11C - β - CFT, 11C Acetate, 11C-CHO, 11C-MET, 11C-FMZ, 11C-DASB, 13N Ammonia, etc
Labeling drugs such as 64Cu, 68Ga, 89Zr, 90Y, 99mTc, 124I, 177Lu, 211At, 225Ac, etc
Control system:
Software interface type: TCP/IP
Communication cable: Ethernet cable
Remote control: Yes
Mobile control: Yes
Computer: Laptop or desktop computer, Windows operating system. Drag and drop interface editing, users can freely edit the new drug interface according to their needs
Working conditions
Environmental temperature:
The ambient temperature ranges from 15 ℃ to 35 ℃; Relative humidity ≤ 85%; The air pressure is not limited.
Gas source requirements:
Nitrogen purity: 99.9%
Compressed air: pressure ranging from 0.6 to 0.8 MPa, with a 0.6 cubic meter gas storage tank. A 12mm diameter air pipe is required from the gas tank to the equipment, and pure air without oil or water is used.
Hot room requirements:
The internal net size can accommodate the synthesizer, with 300mm left in the front and rear directions, 200mm left in the up and down directions, and 200mm left and right directions for maintenance or expansion space.
Power Supply:
There is a 220V 10A three core power socket within and outside the hot room, with a zero to ground voltage of 1 V, grounded and a resistance of ⩽10Ω.
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Address:
Xi 'an Economic and technological Development Zone Jingwei New Town Jingwei small and medium-sized Industrial Park No. 2 Workshop 101, 103
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