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C11 Multifunctional Synthesizer

The PET Cn HPLC multifunctional automated synthesis instrument

Category:

Radiopharmaceutical synthesizer

Key words:

purification

interface

equipped


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Product description

PET Cn HPLC multifunctional synthesizer

The PET Cn HPLC multifunctional automated synthesis instrument is computer-controlled and equipped with a semi preparative HPLC and SPE combination to quickly complete separation and purification, and can be concentrated and solvent removed online for clinical and scientific preparation of C-nuclide labeled drugs. After upgrading, Triflate can be synthesized online, with a large number of drugs prepared, and can synthesize many scientific drugs. It has a simple and easy-to-use user interface, drag and drop interface editing, and users can freely edit the new drug interface according to their needs.

 

System features

• Double reaction tube

• Online concentration and purification

• Equipped with semi preparative HPLC

• Full wavelength ultraviolet detector

• Highly flexible operating modes (fully automatic, semi-automatic, and manual)

• Powerful research programming capabilities and hardware support

• Extremely high reliability

• Integrated cold trap adsorption device

• Compliant with GMP requirements

 

TECHNICAL INDEX

The complete set of equipment includes:

1 synthesizer

1 controller

1 control computer and 1 set of control software

Appearance dimensions:

Synthesizer: 350x510x400mm (height x width x depth) (placed in a hot room)

Controller: 220 × 355x400mm (height x width x depth) (placed outdoors)

HPLC (pump and UV): built-in

Temperature control system:

Heating rate: 25 ℃ to 120 ℃, time 10s to 2s

Temperature accuracy: error<3%

Cooling rate: 120 ℃ to 50 ℃, time 25s ± 2s

Temperature accuracy: error<3%

Interlocking: Hardware and Software

Reaction system:

Reaction system: closed type

Number of heaters: 4

Number of reactors: 3

Radioactive detector:

Type of radioactive detector: GM counter tube or semiconductor

Number of radioactive detectors: 4 or more

Detection range: 1mci~3C

Detection accuracy: error<10%

Typical production varieties and yields (compliant with GMP):

Labeling drugs such as 11C-Acetate, 11C-CHO,  11C-MET, 11C-FMZ, and 11C-Raclopride

Control system:

Software interface type: TCP/IP

Communication cable: Ethernet cable

Remote control: Yes

Mobile control: Yes

Computer: Laptop or desktop computer, Windows operating system. Drag and drop interface editing, users can freely edit the new drug interface according to their needs

 

Working conditions

Environmental temperature:

The ambient temperature ranges from 15 ℃ to 35 ℃; Relative humidity ≤ 85%; The air pressure is not limited.

Gas source requirements:

Nitrogen purity: 299.9%;

Compressed air: pressure ≥ 0.6-0.8 MPa, with a gas storage tank of ≥ 0.6 cubic meters, a 12mm diameter air pipe is required from the gas tank to the equipment, and pure air without oil or water.

Hot room requirements:

The internal net size can accommodate the synthesizer, with 300mm left in the front and rear directions, 200mm left in the up and down directions, and 200mm left and right directions for maintenance or expansion space.

Power Supply:

There is a 220V 10A three core power socket within and outside the hot room, with a zero to ground voltage of 1 V, grounded and a resistance of ≤10Ω.

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